I have a white label, iframe driven website - www.mobcheck.co.uk.
It has a poor quality score for most relevant terms, probably due to iframes and a lack of content, im not sure. Here is a good post on why iframes are bad for seo/ppc:
[url removed, login to view]
So, the mission is, get a great quality score for relevent terms on the index page and the main handset pages. If you think you would like to have a go, please get in touch.